Flow Rate Equation:
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The Agilent GC Flow Calculator estimates the flow rate through a gas chromatography column based on column dimensions and linear velocity. It's essential for method development and optimization in gas chromatography.
The calculator uses the flow rate equation:
Where:
Explanation: The equation calculates volumetric flow rate by multiplying column cross-sectional area by linear velocity.
Details: Accurate flow rate calculation is crucial for proper carrier gas selection, retention time consistency, and optimal chromatographic separation.
Tips: Enter column length in meters, diameter in millimeters, and velocity in cm/s. All values must be positive numbers.
Q1: Why is flow rate important in GC?
A: Flow rate affects retention times, peak shapes, and separation efficiency. Proper flow ensures consistent results and prevents column damage.
Q2: What are typical flow rates for GC?
A: For 0.25mm ID columns: 1-2 ml/min; 0.32mm ID: 2-4 ml/min; 0.53mm ID: 5-10 ml/min (varies by application).
Q3: How does column diameter affect flow rate?
A: Flow rate increases with the square of column diameter - doubling diameter quadruples flow rate at same velocity.
Q4: What's the relationship between flow rate and velocity?
A: Linear velocity is flow rate divided by column cross-sectional area. Higher flow rates increase velocity.
Q5: Should I use this for pressure calculations?
A: No, this calculates volumetric flow only. Pressure depends on additional factors like gas type and temperature.