Agilent Pressure Flow Model:
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The Agilent Pressure Flow Model is based on the Hagen-Poiseuille equation, which describes the relationship between pressure difference, flow rate, and tube dimensions for laminar flow of Newtonian fluids in cylindrical tubes.
The calculator uses the Hagen-Poiseuille equation:
Where:
Explanation: The equation shows that flow rate is proportional to the fourth power of the radius, making tube diameter the most critical factor in determining flow.
Details: Accurate flow rate calculation is essential for designing fluidic systems, chromatography applications, and understanding pressure-flow relationships in analytical instruments.
Tips: Enter all values in consistent units (cm for dimensions, dyn/cm² for pressure, poise for viscosity). Ensure all values are positive and non-zero.
Q1: What are the assumptions of this model?
A: The model assumes laminar flow, Newtonian fluid, no-slip boundary conditions, steady-state flow, and a long cylindrical tube with constant circular cross-section.
Q2: When is this model not applicable?
A: Not valid for turbulent flow, non-Newtonian fluids, very short tubes, or tubes with non-circular cross-sections.
Q3: How does temperature affect the calculation?
A: Temperature primarily affects viscosity. Use the correct viscosity value for your operating temperature.
Q4: What is the typical range for HPLC flow rates?
A: Common HPLC flow rates range from 0.1 to 5 mL/min, depending on column dimensions and application requirements.
Q5: How can I convert between different pressure units?
A: 1 bar = 10⁶ dyn/cm², 1 atm = 1.01325 bar, 1 psi ≈ 68947.6 dyn/cm².